2008年3月26日 星期三

Transport in Mammal

 

A) Heart

1) Mechanism of heart beating :

  • Heart beat simultancously and rhythmic to pump blood along blood vascular system

heart_mechanism

 

2) Nerves control of heartbeat :

未命名

3) Cardiac cycle :

 HD002 cardiac cycle 2007r1

* Blood flow from high pressure to low pressure

B) Blood Vessel :

Structural Adaptation of Blood Vessel :

1) Arteries :

  1. Thick Wall : Withstrand high blood pressure
  2. Thick elastic fibres : Recoil after the dilution, push blood further away
  3. Nerve supply : regulate the diameter of the arteries

artery elastic_leave

2) Vein :

  1. Valve : prevent backflow
  2. Large lumen : reduce resistance
  3. Attached by skeletal muscle : force blood forward

HD002 cardiac cycle 2007r1

artery-vein

3) Capillary :

  1. Protein channel : allow small molecule pass through
  2. Thin wall : rapid diffusion
  3. Small diameter : slow blood flow allow longer time to exchange
  4. Network of capillary : increase surface area
  5. Close to tissue : shorten the distance

capillary_cs

simple_squamous_capillary

illu_lymph_capillary

 

C) Blood :

1) Oxygen dissociation curve :

5531-320px-hb-saturation-curve-hemoglobin
  • At high oxygen tension, e.g: lung surface, % of saturated haemoglobin is near 95, this facilitates the uptake of O2 as oxyhaemoglobin.
  • At tissue, a slight decrease of oxygen tension result in rapid drop in dissocation of oxyhaemoglobin , which oxygen will diffuse out rapidly.

 

2) Bohr effect :

bohrcurve
  • At high CO2 tension, the haemoglobin is less efficient in taking up oxygen
  • it can cause by increase [CO2], decrease pH and increase temperature

 

(CO2 diffuse forms carbonic acid, carbonic acid dissoicate to liberate H+, H+ combine with haemoglobin to displace O2 )

3) Adaptation of organism :

For organism living in low oxygen tension atmosphere :

Deermi6
  • It allows organism to attend high % of saturated haemoglobin at lower atmosphere oxygen tension.

 

For high metabolic organism :

fig1-19
  • It allows organism to release more oxygen at tissue

 

D) Lymph :

1) Mechanism of forming lymph :

  1. High blood pressure at the arteries end of capillary, due to (1)pumping action of heart and (2)high pressure of artery
  2. The high hydrostatic pressure exceeds the osmotic pressure in blood, which force all constituents of blood plasma except large protein out to the intercellular space through capillaries wall by filtration forming tissue fluid.
  3. Most of the tissue fluid is drawn back into capillary by osmosis due to high water potential of the tissue fluid at the intercellular space the rest of them is forced into the lymphatic vessel forming lymph.

2) Significant of lymph :

  1. Forming linkage between tissue fluid and blood vascular system
  2. Transport absorbed fat from lacteals
  3. lymph node (a) produce lymphocytes which produce antibody to neutrolize the effect of antigen, thus ,it is a part of immune system. (b) phagocyte engulf bacteria and foreign particle in lymph

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