Fluid-mosaic model
Permeability
A) Not allow to pass:
- inner layer of the phospholipid layer, which is hydrophobic, forms a physical barrier to those polar substance
B) Allow to pass:
- phospholipid bilayer allows fat soluble molecules and small uncharged molecule e.g:O2,CO2 to diffuse freely pass through
- channel protein form open pores for (facilitated) diffusion of small polar substance to pass through
C) Carrier protein:
- carrier protein bind with specific molecule and bring them to the opposite side of the membrane
- carrier protein allow facilitated diffusion of some molecule
Factors affecting the permeability
- Temperature
- fat soluble substance
- charge of the polar particule
- lipid visocity
Function
- Compartmentalization
- Control exchange
- Site of membrane-binded enzymatic reaction
- recognition
- cell and organic identity
- endocytosis
- extocytosis
- myelin sheath insulutes
* try to think the composition of cell membrane first
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